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One-pot synthesis of 2-aminoquinazolinones through sequential microwave irradiation and electrosynthesis

When Miss Khuyen T. Nguyen, a Ph.D. student, posed a simple question: “Why don’t we combine Microwave Chemistry and Electrosynthesis into a one-pot process?” As it turns out, this simple idea led to a much faster way to build compound libraries.  The work resulted in the development of a one-pot sequential microwave electrosynthesis strategy for the …

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Engineering Gap-Enhanced Raman Tags for High-Performance Security Inks

This research developed a security ink based on gap-enhanced Raman tags (GERTs) that is invisible to the naked eye but detectable through highly specific SERS signals using Raman spectroscopy. The optimized ink produces strong, uniform, and stable Raman signals. By tuning the concentrations of HAuCl4 and HEPES, the researchers balanced SERS enhancement and colloidal stability. …

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Machine-free Processing of Plant-based Textured Meat from Natural Fibers: A Route to Sustainable Future Food

Amid the growing global demand for sustainable food systems, reduced carbon emissions, and healthier dietary choices, the development of plant-based meat that can closely replicate both the sensory properties and structural complexity of animal meat remains a significant challenge. In particular, recreating the fibrous texture that mimics muscle tissue is difficult, as current technologies typically …

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Magnetic biochar composite for water purification

Researchers have developed an advanced adsorbent derived from sugarcane bagasse-an abundant agricultural waste-by modifying it with magnetic Fe3O4-ZnO nanoparticles and a deep eutectic solvent (DES). The developed material demonstrates high efficiency in removing key water contaminants, including: Diclofenac (pharmaceutical pollutant), Cr(VI) (toxic oxyanion), and Pb(II) (heavy metal). It also exhibits significantly enhanced adsorption capacity compared …

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Ultrasensitive Photothermal/Fluorescent Paper-Based Microfluidic Immunosensor for Nuclear Matrix Protein 22 (NMP22) Quantification in Human Urine Samples for Rapid Diagnosis of Bladder Cancer

The first paper-based microfluidic sensing platform has been successfully developed for sensitive and selective monitoring of NMP22 levels in human urine samples for rapid bladder cancer diagnostics, integrating microfluidics, optical nanomaterials, biopolymer immobilization, and immunological technique, led by Dr. Kawin Khachornsakkul and Assist. Prof. Dr. Waleed Alahmad. The developed immunosensor can monitor NMP22 levels with …

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Bifunctional catalysts for one-pot CO2 conversion into value-added chemicals

Carbon dioxide (CO2) is not only a major greenhouse gas but also an abundant C1 feedstock for producing high-value cyclic carbonates used in batteries and polymers. Typically, the direct one-pot conversion of alkenes and CO2 requires complex multi-component catalytic systems. This research focuses on the development of single-component bifunctional catalysts (Co-mSiO2 @[Py-R][X]) by modifying mesoporous …

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Edible scaffolds enriched with soy protein facilitating myogenic progression of C2C12 cells with potential for cultured meat applications

To overcome the problems of livestock farming, cultured meat technologies have been developed. The construction of cultured meat requires edible, biocompatible, and nutrition-rich scaffolds that not only support cell growth but should also align with sustainable, animal-free principles. This research led by the postdoctoral researcher, Ms.Yuwaporn Pinyakit, Prof.Dr.Voravee Hoven, and Dr.Chanat Aonbangkhen, in collaboration with …

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Smartphone-Based Hydrogen Sulfide Detection for Safer Environmental Monitoring

Hydrogen sulfide (H₂S), commonly known as the “rotten-egg gas,” is a toxic gas frequently found in wastewater and organic decomposition processes. Even at low concentrations, H₂S can pose risks to human health, making rapid and accessible detection methods essential for environmental monitoring.Researchers from the Environmental Analysis Research Unit (EARU) have developed a simple method for …

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Green ultrasound-assisted extraction for efficient carotenoid profiling of calamansi

Unlocking the golden secrets of Calamansi (Citrofortunella microcarpa), a research team led by Prof. Dr. Thanit Praneenararat has pioneered a high-efficiency, eco-friendly path to extracting its hidden antioxidants. While this tiny citrus powerhouse—famed for its signature orange-lime zest—is a rising star in product development, its specific carotenoid profile remained a mystery until the team utilized …

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Colchicine-derived anticancer molecules with up to 2000-fold selectivity for cancer cells over normal cells

 A drug discovery research team led by Assoc. Prof. Dr. Tanatorn Khotavivattana from the Department of Chemistry, Faculty of Science, Chulalongkorn University has developed a new class of anticancer molecules by modifying the structure of colchicine, a natural compound known to inhibit cell division by binding to the tubulin protein that forms microtubules inside cells. …

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