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Artificial three-dimensional skin from fish gelatin-hyaluronic acid porous scaffold

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Artificial three-dimensional (3D) skin has been used as an alternative material for toxicity testing, studying skin diseases, and skin tissue engineering. The 3D skin can be fabricated using supporting materials that facilitate cell attachment, promote nutrients and air permeation, and eventually accommodate 3D cellular construction. Herein, fish gelatin-hyaluronic acid porous scaffold were employed as the …

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Discovery of New Alpha-Glucosidase Inhibitors from Cannabis Leaves Leading to Structural and Mechanistic Insights

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Thailand has permitted the use of Cannabis sativa for medical purposes, creating opportunities for broader research on its potential applications. In this study, 11 new compounds of the cannabinoid and spiroindane classes were identified. These include substances with inhibitory activity against α-Glucosidase, an enzyme associated with diabetes. Molecular docking studies, supported by the research group …

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One class self-organizing maps with Monte Carlo permutation for gemstone classification using Raman spectroscopy

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Accurately identifying gemstones is important for authentication and quality control. In this study, we developed an artificial intelligence method that uses self-organizing maps (SOMs) combined with Monte Carlo testing to classify gemstones from their Raman vibrational patterns. The model was optimized for map size and training cycles, and its reliability was evaluated through repeated random …

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Game-Changing Hepatitis B Virus Electrochemical Sensor Developed from Laser-Induced Graphene

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 Dr. Pumidech Puthongkham’s research group has been pioneered the application of Laser-Induced Graphene (LIG) in electrochemical biosensors in our department! We’ve just unveiled a high-performance immunosensor for Hepatitis B surface antigen (HBsAg) detection. Why it’s a Breakthrough:  Ultra-Sensitive & Fast: Functionalizing more carboxyl group on LIG electrode enhanced HBV antibody immobilization, yielding an incredibly low …

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Modified MOF catalysts: CO2 to value-added products

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This research focuses on the design and modification of high surface area, porous materials known as metal-organic frameworks (MOFs). The objective is to utilize these materials as catalysts to convert carbon dioxide (CO2) into high-value cyclic carbonates, which are crucial for the polymer and battery industries. MOFs typically suffer from diffusion limitations because their pores …

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Assoc. Prof. Dr. Stefano Cinti

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Associate Professor Dr. Stefano Cinti stefano.cinti@unina.it Department of Pharmacy, University of Naples Federico II, Italy electrochemical sensors, paper-based devices, nanomotors, and nanomaterials Welcome to the Lab

Professor Dr. Syuji Fujii

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Professor Dr. Syuji Fujii syuji.fujii@oit.ac.jp Department of Applied Chemistry, Faculty of Engineering, Osaka Institute of Technology, Japan colloid and interfacial chemistry, polymer chemistry https://research-db.oit.ac.jp/html/100000883_en.html

A disubstituted aniline probe for enhanced peroxidase-based proximal protein labelling

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 Proteins are biomolecules essential for cellular functions, including cell signaling and regulation. Protein misfolding or mislocalisation can result in various diseases. Peroxidase-mediated proximity labelling has emerged as a powerful tool for studying subcellular proteome and protein–protein interactions. However, the traditional probe, biotin-phenol, suffers from limitations including low protein enrichment efficiency, and the formation of oxidised …

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Polarity and Viscosity-Sensitive Fluorescent Probe for Lipid Droplet Imaging

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This study presents a new fluorescent compound that responds sensitively to environmental polarity and viscosity. The compound is biocompatible, shows low toxicity, and selectively binds to lipid droplets in living cells, enabling precise monitoring of intracellular changes. These results highlight its potential as a powerful tool for exploring biological processes and microenvironmental properties.  Read More …

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