ธนธรณ์ ขอทวีวัฒนา

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รองศาสตราจารย์ ดร. ธนธรณ์ ขอทวีวัฒนา

  • ห้อง 1319 อาคารมหามกุฎ ภาควิชาเคมี คณะวิทยาศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย แขวงวังใหม่ เขตปทุมวัน กทม. 10330
  • 02-2187621
Research Summary​

การศึกษา

  • [2017] DPhil in Organic Chemistry, University of Oxford
  • [2013] MChem Chemistry, University of Oxford

ประสบการณ์การทำงาน

  • [2024 - present] Associate Professor at the Department of Chemistry, Faculty of Science, Chulalongkorn University
  • [2020 - 2024] Assistant Professor at the Department of Chemistry, Faculty of Science, Chulalongkorn University
  • [2017 - 2020] Lecturer at the Department of Chemistry, Faculty of Science, Chulalongkorn University

หัวข้องานวิจัยในปัจจุบัน

  • Drug discovery
  • Organofluorine chemistry
  • Structural modification of natural products via total/semi synthesis for enhanced biological activities

Research Themes

Development of electrochemical sensors and electroanalytical methods for detecting various active compounds, with applications in medical/healthcare, environmental, and food safety sectors.

ทุนและรางวัล

  • [2013] GlaxoSmithKline Award
  • [2013 – 2015] SCI Messel Scholarship
  • [2012] Eisai Limited Undergraduate Award, University of Oxford, UK
  • [2012] Gibbs Prize – Proxime Accessit, University of Oxford, UK
  • [2012] Phillips Prize, University of Oxford, UK
  • [2011] Exhibitioner Scholarship, Merton College, UK
  • [2011] Nuffield Foundation Undergraduate Research Bursaries, University of Oxford, UK
  • [2011] Postmaster Scholarship, Merton College, UK
  • [2010] Bruker UK Limited Prize, University of Oxford, UK
  • [2010] Turbutt Prize, University of Oxford, UK

ผลงานตีพิมพ์

•FMO-guided design of darunavir analogs as HIV-1 protease inhibitors. Scientific Reports. 2024. Cited 4
•Design, Synthesis, and Biological Evaluation of Darunavir Analogs as HIV-1 Protease Inhibitors. ACS Bio and Med Chem Au. 2024. Cited 0
•A facile one-pot iodine-mediated synthesis of cannabinol and derivatives, and their intestinal epithelial barrier protective effect. Tetrahedron. 2024. Cited 0
•Electrochemical Detection of Melatonin at Nano-Sized Highly Boron-Doped Diamond Electrode. Journal of the Electrochemical Society. 2024. Cited 0
•Machine learning-guided design of potent darunavir analogs targeting HIV-1 proteases: A computational approach for antiretroviral drug discovery. Journal of Computational Chemistry. 2024. Cited 4
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